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PMID: 11844146 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Seven single nucleotide substitutions in human Fc(gamma) receptor IIB gene.

Tissue antigens ·Vol. 58 ·No. 5 ·2001-11-00 ·Pages 339-42

Yasuda K, Sugita N, Yamamoto K, Kobayashi T, Yoshie H

Abstract

Variation screening for the immunoglobulin G Fc receptor IIB (Fc(gamma)RIIB) gene was performed with the genomic DNA from 100 healthy Japanese subjects. We identified 3 non-synonymous and 2 synonymous substitutions and 2 single-nucleotide polymorphisms in an intron region. These substitutions were found to be located in the ligand-binding domain and the intron, which might alter the function of Fc(gamma)RIIb.

MeSH Terms

Amino Acid Motifs Antigens, CD/chemistry,genetics Base Sequence DNA Primers Humans Molecular Sequence Data Polymorphism, Single Nucleotide Receptors, IgG/chemistry,genetics Sequence Analysis, DNA

Chemicals

Antigens, CD DNA Primers Fc gamma receptor IIB Receptors, IgG

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Yasuda K

Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Sugita N

Yamamoto K

Kobayashi T

Yoshie H

Article Info

Journal

Tissue antigens

Abbr.

Tissue Antigens

ISSN

0001-2815

DOI

10.1034/j.1399-0039.2001.580509.x

Published

2001-11-00

Pages

339-42

Language

English

Region

England

NLM ID

0331072

Subset

Databases

GENBANK

AB060144, AB060145, AB060146, AB060147, AB060148, AB060149, AB060150

External Links

PubMed source DOI: 10.1034/j.1399-0039.2001.580509.x View journal details

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Seven single nucleotide substitutions in human Fc(gamma) receptor IIB gene.

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