Deacetylase enzymes: biological functions and the use of small-molecule inhibitors.

Amino Acid Sequence Enzyme Inhibitors/metabolism Fungal Proteins/metabolism Histone Deacetylase 1 Histone Deacetylase 2 Histone Deacetylase Inhibitors Histone Deacetylases/chemistry,genetics,metabolism Histones/genetics,metabolism Humans Molecular Sequence Data Protein Binding Repressor Proteins Silent Information Regulator Proteins, Saccharomyces cerevisiae Sirtuin 1 Sirtuin 2 Sirtuins Structure-Activity Relationship Trans-Activators/antagonists & inhibitors,chemistry,genetics,metabolism Transcription, Genetic

Enzyme Inhibitors Fungal Proteins Histone Deacetylase Inhibitors Histones Repressor Proteins Silent Information Regulator Proteins, Saccharomyces cerevisiae Trans-Activators SIR2 protein, S cerevisiae SIRT1 protein, human Sirtuin 1 Sirtuin 2 Sirtuins HDAC1 protein, human Histone Deacetylase 1 Histone Deacetylase 2 Histone Deacetylases