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题目:
Temperature dependence in proliferation of tetraploid Meth-A cells in comparison with the parent diploid cells.
作者:
Fujikawa-Yamamoto(K),Wang(S),Yamagishi(H),Miyagoshi(M)
状态:
发布时间2002-02-07 , 更新时间 2006-11-15
期刊:
Cell Struct Funct
摘要:
The temperature dependency for the growth of tetraploid Meth-A cells established from diploid cells was examined in comparison with the parent diploid cells. Proliferation of the tetraploid cells was markedly suppressed below 35 degrees C. At above 40 degrees C, both the diploid and tetraploid Meth-A cells ceased growing. Flow cytometry (FCM) analysis showed that the hyperploid cell fraction increased in the tetraploid Meth-A cell population at low temperatures. The fluidity of cell membranes at different temperatures was measured by means of electron spin resonance (ESR), and it was almost the same between the diploid and tetraploid Meth-A cells. It was suggested that the decreased proliferation below 35 degrees C of the tetraploid Meth-A cells might be due to the increased volume of the cells.
语言:
eng
DOI:

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