Proton release as a modulator of presynaptic function.

Neuron ·Vol. 32 ·No. 6 ·2001-12-20 ·Pages 960-2

Traynelis SF, Chesler M

Abstract

In this issue of Neuron, DeVries (2001) describes experiments suggesting that acidification of the synaptic cleft can reduce Ca2+ channel activity and thereby act as a brake on tonic synaptic release of glutamate from cone cells. This work hints at a potentially important new facet to the regulation of synaptic transmission.

MeSH Terms

Animals Presynaptic Terminals/physiology Protons Synaptic Transmission/physiology

Chemicals

Protons

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Traynelis S F

Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, 1510 Clifton Road, Atlanta, GA 30322, USA.

Chesler M

Article Info

Journal

Neuron

Abbr.

Neuron

ISSN

0896-6273

DOI

10.1016/s0896-6273(01)00549-9

Published

2001-12-20

Pages

960-2

Language

English

Region

United States

NLM ID

8809320

Subset

Corrections

CommentOn

PMID: 11754841

External Links

PubMed source DOI: 10.1016/s0896-6273(01)00549-9 View journal details

Analysis Services

Proton release as a modulator of presynaptic function.

Contact

WeChat Official Account