Familial translocation, t(2;5) (p23; g31).

Clinical genetics ·Vol. 8 ·No. 2 ·1975-08-00 ·Pages 112-6

Osztovics M, Kiss P

Abstract

A reciprocal translocation, t(2;5) (p23; q31) was found in healthy individuals through two generations of a family. The balanced aberration resulted in a derivate chromosome 2 in two malformed offspring in the third generation. The family was ascertained through the two unbalanced carriers whose phenotype abnormalities resembled those of two other offspring who died prior to the cytogenetic examination.

MeSH Terms

Adult Child Chromosome Aberrations Chromosomes, Human, 1-3 Chromosomes, Human, 4-5 Female Heart Defects, Congenital/genetics Humans Infant Infant, Newborn Male Microcephaly/genetics Pedigree Translocation, Genetic

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Osztovics M

Kiss P

Article Info

Journal

Clinical genetics

Abbr.

Clin Genet

ISSN

0009-9163

Published

1975-08-00

Pages

112-6

Language

English

Region

Denmark

NLM ID

0253664

Subset

External Links

PubMed source View journal details

Analysis Services

Familial translocation, t(2;5) (p23; g31).

Contact

WeChat Official Account