Abstract
The GenBank sequence database incorporates publicly available DNA sequences of more than 105 000 different organisms, primarily through direct submission of sequence data from individual laboratories and large-scale sequencing projects. Most submissions are made using the BankIt (web) or Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Data exchange with the EMBL Data Library and the DNA Data Bank of Japan helps ensure comprehensive worldwide coverage. GenBank data is accessible through NCBI's integrated retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical literature via PubMed. Sequence similarity searching is provided by the BLAST family of programs. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. NCBI also offers a wide range of World Wide Web retrieval and analysis services based on GenBank data. The GenBank database and related resources are freely accessible via the NCBI home page at http://www.ncbi.nlm.nih.gov.
MeSH Terms
Animals
Base Sequence
Data Collection
Databases, Nucleic Acid
Expressed Sequence Tags
Genome
Humans
Information Storage and Retrieval
Internet
National Library of Medicine (U.S.)
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid
Sequence Tagged Sites
United States
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Benson Dennis A
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA. dab@ncbi.nlm.nih.gov
Karsch-Mizrachi Ilene
Lipman David J
Ostell James
Rapp Barbara A
Wheeler David L
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