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题目:: HL-A in cancer family "N".
作者:: Lynch(H T),Thomas(R J),Terasaki(P I),Ting(A),Guirgis(H A),Kaplan(A R),Magee(H),Lynch(J),Kraft(C),Chaperon(E)
状态:: 发布时间1975-12-29 , 更新时间 2006-11-15
期刊:: Cancer
摘要:: Actual HL-A typing has been performed on 115 members of cancer family N, a large kindred (over 1000 members ascertained) showing the findings consistent with the cancer family syndrome. In the cancer-prone line (branches C and D) of the family, 20 of 21 members with cancer had one HL-A haplotype, HL-A2-HL-A12 (relative odds = 6.30), including some decreased family members who had haplotypes assigned. Eleven of 12 family members with cancer in branches C and D, actually typed, had HL-A2-HL-A12 (relative odds = 6.06). The single exception showing cancer and another haplotype in branch D is a child of a family member with haplotype HL-A2-HL-A12.
语言:: eng
DOI:

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