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PMID: 11719183 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Review

Reconstructing/deconstructing the earliest eukaryotes: how comparative genomics can help.

Cell ·Vol. 107 ·No. 4 ·2001-11-16 ·Pages 419-25

Dacks JB, Doolittle WF

Abstract

We could reconstruct the evolution of eukaryote-specific molecular and cellular machinery if some living eukaryotes retained primitive cellular structures and we knew which eukaryotes these were. It's not clear that either is the case, but the expanding protist genomic database could help us in several ways.

MeSH Terms

Animal Population Groups/genetics Animals Archaea/genetics Bacteria/genetics Bacterial Proteins/genetics Consensus Sequence Escherichia coli Proteins Eukaryota/metabolism Eukaryotic Cells/cytology Evolution, Molecular Expressed Sequence Tags Fungi/genetics Genomics Golgi Apparatus/enzymology Introns/genetics Microsporidia/genetics Mitochondria Phylogeny Plants/genetics Species Specificity Spliceosomes Trichomonas/genetics

Chemicals

Bacterial Proteins Escherichia coli Proteins MreB protein, E coli

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Dacks J B

Program in Evolutionary Biology, Canadian Institute for Advanced Research, Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.

Doolittle W F

Article Info

Journal

Cell

Abbr.

Cell

ISSN

0092-8674

DOI

10.1016/s0092-8674(01)00584-0

Published

2001-11-16

Pages

419-25

Language

English

Region

United States

NLM ID

0413066

Subset

External Links

PubMed source DOI: 10.1016/s0092-8674(01)00584-0 View journal details

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Reconstructing/deconstructing the earliest eukaryotes: how comparative genomics can help.

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