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PMID: 1171079 Published · ppublish English Journal Article

Translocation +(7p+; Bq-) associated with recurrent abortion.

Humangenetik ·Vol. 28 ·No. 1 ·1975-05-26 ·Pages 83-6

Körner H, Agricola H, Bayer H

Abstract

A balanced translocation was found in a normal female with a history of four abortions. On the basis of the Giemsa-banding pattern the abnormality was interpreted as to be a translocation of a part of the long arm of chromosome 13 to the short arm of chromosome some 7:t(7;13)(7qter leads to 7p22::13q14 leads to 13qter;13q14 leads to 13pter::7p22 leads to 7 pter). Problems in genetic counseling are discussed with respect to this case.

MeSH Terms
Abortion, Habitual/genetics Chromosome Aberrations Chromosomes, Human, 13-15 Chromosomes, Human, 6-12 and X Female Genetic Counseling Humans Karyotyping Pregnancy Translocation, Genetic
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Körner H
Agricola H
Bayer H
References (6)
6 references, click to expand
  1. Human genetics.
    Annu Rev Genet. 1973;7:435-72 PMID: 4131531
  2. Increased frequency of chromosomal anomalies in abortions after induced ovulation.
    Lancet. 1973 Mar 24;1(7804):679-80 PMID: 4121900
  3. Chromosome preparations of leukocytes cultured from human peripheral blood.
    Exp Cell Res. 1960 Sep;20:613-6 PMID: 13772379
  4. Identification of individual chromosomes in the human karyotype by their banding pattern after proteolytic digestion.
    Humangenetik. 1972;15(3):249-52 PMID: 5082092
  5. [The role of parental translocations in cases of repeated miscarriages].
    Rev Fr Gynecol Obstet. 1973 Nov;68(11):655-60 PMID: 17474223
  6. [Inherited translocation t(4q minus;18q plus) with unbalanced progeny of different types (author's transl)].
    Humangenetik. 1974 Mar 28;21(4):315-21 PMID: 4135065
Article Info
Journal
Humangenetik
Abbr.
Humangenetik
ISSN
0018-7348
Published
1975-05-26
Pages
83-6
Language
English
Region
Germany
NLM ID
7607154
Subset
IM
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