Decomposition of unsaturated fatty acid hydroperoxides by hemoglobin: Structures of major products of 13L-hydroperoxy-9,11-octadecadienoic acid.

Lipids ·Vol. 10 ·No. 2 ·1975-02-00 ·Pages 87-92

Hamberg M

Abstract

13L-hydroperoxy-9, 11-octadecadienoic acid was decomposed rapidly in the presence of hemoglobin. The product consisted of five major compounds, i.e. 13-keto-9, 11-octadecadienoic acid, 13L-hydroxy-9, 11-octadecadienoic acid, erythro-11-hydroxy-12, 13-epoxy-9-octadecenoic acid, threo-11-hydroxy-12, 13-epoxy-9-octadecenoic acid, and 9 DL-hydroxy-12, 13-epoxy-10-octadecenoic acid.

MeSH Terms

Animals Cattle Chromatography, Gas Chromatography, Thin Layer Fatty Acids, Unsaturated/metabolism Hemoglobins Mass Spectrometry Methemoglobin Oxyhemoglobins Peroxides/metabolism Spectrophotometry, Ultraviolet Stereoisomerism

Chemicals

Fatty Acids, Unsaturated Hemoglobins Oxyhemoglobins Peroxides Methemoglobin

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Hamberg M

References (3)

3 references, click to expand

An anaerobic reaction between lipoxygenase, linoleic acid and its hydroperoxides.
Biochem J. 1971 Apr;122(3):327-32 PMID: 5165730
Steric analysis of hydroperoxides formed by lipoxygenase oxygenation of linoleic acid.
Anal Biochem. 1971 Oct;43(2):515-26 PMID: 5168775
Intracellular mechanisms for the decomposition of a lipid peroxide. I. Decomposition of a lipid peroxide by metal ions, heme compounds, and nucleophiles.
Can J Biochem. 1969 May;47(5):485-92 PMID: 5787688

Article Info

Journal

Lipids

Abbr.

Lipids

ISSN

0024-4201

DOI

10.1007/BF02532161

Published

1975-02-00

Pages

87-92

Language

English

Region

United States

NLM ID

0060450

Subset

External Links

PubMed source DOI: 10.1007/BF02532161 View journal details

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Decomposition of unsaturated fatty acid hydroperoxides by hemoglobin: Structures of major products of 13L-hydroperoxy-9,11-octadecadienoic acid.

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