Impairment of CYP3A4 capacity in patients receiving danazol therapy: examination on oxidative cortisol metabolism.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme ·Vol. 33 ·No. 10 ·2001-10-00 ·Pages 628-30

Konishi H, Takenaka A, Minouchi T, Yamaji A

Abstract

暂无摘要

MeSH Terms

Adult Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System/metabolism Danazol/adverse effects Enzyme Activation/drug effects Estrogen Antagonists/adverse effects Female Humans Hydrocortisone/analogs & derivatives,metabolism,urine Middle Aged Mixed Function Oxygenases/metabolism Oxidation-Reduction Pilot Projects

Chemicals

Estrogen Antagonists 6 beta-hydroxycortisol Cytochrome P-450 Enzyme System Mixed Function Oxygenases CYP3A protein, human Cytochrome P-450 CYP3A CYP3A4 protein, human Danazol Hydrocortisone

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Konishi H

Department of Hospital Pharmacy, Shiga University of Medical Science, Otsu, Japan. konishi@belle.shiga-med.ac.jp

Takenaka A

Minouchi T

Yamaji A

Article Info

Journal

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Abbr.

Horm Metab Res

ISSN

0018-5043

DOI

10.1055/s-2001-17912

konishi@belle.shiga-med.ac.jp

Published

2001-10-00

Pages

628-30

Language

English

Region

Germany

NLM ID

0177722

Subset

External Links

PubMed source DOI: 10.1055/s-2001-17912 View journal details

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Impairment of CYP3A4 capacity in patients receiving danazol therapy: examination on oxidative cortisol metabolism.

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