A TPR motif cofactor contributes to p300 activity in the p53 response.

Acetyltransferases/genetics,metabolism Amino Acid Motifs Amino Acid Sequence Apoptosis/physiology Carrier Proteins/chemistry,genetics,metabolism Cell Cycle Proteins/genetics,metabolism Cell Line Etoposide/pharmacology Gene Expression Regulation Genes, Reporter Histone Acetyltransferases Humans Immunoblotting Macromolecular Substances Molecular Sequence Data Multiprotein Complexes Nuclear Proteins/genetics,metabolism Nucleic Acid Synthesis Inhibitors/pharmacology Precipitin Tests Protein Binding Protein Structure, Tertiary Proto-Oncogene Proteins/genetics,metabolism Proto-Oncogene Proteins c-mdm2 Radiation, Ionizing Serine Endopeptidases Stress, Physiological Trans-Activators/genetics,metabolism Transcription Factors Transfection Tumor Suppressor Protein p53/genetics,metabolism Two-Hybrid System Techniques Ultraviolet Rays p300-CBP Transcription Factors

Carrier Proteins Cell Cycle Proteins JMY protein, human Macromolecular Substances Multiprotein Complexes Nuclear Proteins Nucleic Acid Synthesis Inhibitors Proto-Oncogene Proteins Strap protein Trans-Activators Transcription Factors Tumor Suppressor Protein p53 Etoposide Acetyltransferases Histone Acetyltransferases p300-CBP Transcription Factors p300-CBP-associated factor MDM2 protein, human Proto-Oncogene Proteins c-mdm2 SRAP protein, Luidia foliolata Serine Endopeptidases