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PMID: 1150278 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Implications of somatic recombination and sister chromatid exchange in Bloom's syndrome and cells treated with mitomycin C.

Humangenetik ·Vol. 28 ·No. 3 ·1975-07-23 ·Pages 191-6

Comings DE

Abstract

It is suggested that the somatic recombination observed in Bloom's syndrome and cells treated with mitomycin C may be the result of selection for recombination events that can occur only between homologous segments of DNA, rather than a result of somatic pairing in the nucleus.

MeSH Terms
Abnormalities, Multiple/genetics Chromatids Crossing Over, Genetic/drug effects Dwarfism Facial Dermatoses/genetics Humans Mitomycins/pharmacology Recombination, Genetic Syndrome Telangiectasis/genetics
Chemicals
Mitomycins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Comings D E
References (45)
45 references, click to expand
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Article Info
Journal
Humangenetik
Abbr.
Humangenetik
ISSN
0018-7348
Published
1975-07-23
Pages
191-6
Language
English
Region
Germany
NLM ID
7607154
Subset
IM
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