Polymorphism of red cell glyoxalase I (EI: 4.4.1.5); a new genetic marker in man. Investigation of 169 mother-child combinations.

Humangenetik ·Vol. 27 ·No. 2 ·1975-00-00 ·Pages 141-3

Kömpf J, Bissbort S, Gussmann S, Ritter H

Abstract

The polymorphism of glyoxalase I was investigated in 169 mother-child combinations from southwestern Germany. Glyoxalase I (GLO) has 3 common phenotypes: GLO 1, GLO 2-1, and GLO 2. The results are in good agreement with the formal hypothesis: Two alleles GLO1 and GLO2 at an autosomal locus. The GLO1 gene frequency was estimated to be 0.39. From the electrophoretic pattern the GLO-molecule appears to consist of two subunits.

MeSH Terms

Erythrocytes/enzymology Female Gene Frequency Germany, West Glutathione Glyoxal Humans Lyases Molecular Biology Polymorphism, Genetic

Chemicals

Glyoxal Lyases Glutathione

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Kömpf J

Bissbort S

Gussmann S

Ritter H

References (2)

2 references, click to expand

Electrophoretic study of glutathione reductase in human erythrocytes and leucocytes.
Nature. 1968 Jan 20;217(5125):256-8 PMID: 4384274
Population genetics of red cell galactose-1-phosphate-uridyl-transferase (EC:2.7.7.12).
Humangenetik. 1972;17(1):79-80 PMID: 4647724

Article Info

Journal

Humangenetik

Abbr.

Humangenetik

ISSN

0018-7348

DOI

10.1007/BF00273329

Published

1975-00-00

Pages

141-3

Language

English

Region

Germany

NLM ID

7607154

Subset

External Links

PubMed source DOI: 10.1007/BF00273329

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Polymorphism of red cell glyoxalase I (EI: 4.4.1.5); a new genetic marker in man. Investigation of 169 mother-child combinations.

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