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PMID: 11455441 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Developmental expression of the Xenopus Iroquois-family homeobox genes, Irx4 and Irx5.

Development genes and evolution ·Vol. 211 ·No. 5 ·2001-05-00 ·Pages 257-60

Garriock RJ, Vokes SA, Small EM, Larson R, Krieg PA

Abstract

We have isolated and characterized the developmental expression of the Xenopus Iroquois 4 (Irx4) and Iroquois 5 (Irx5) homeodomain transcription factors. Irx4 is expressed in a subset of cells in the neural retina and the developing hindbrain and also, specifically, in the ventricle of the heart. Xenopus Irx5 is expressed in the developing midbrain, hindbrain, neural tube, and also in the retina.

MeSH Terms

Amino Acid Sequence Animals Brain/embryology,metabolism Conserved Sequence Gene Expression Regulation, Developmental Heart/embryology Homeodomain Proteins/genetics,physiology Humans Molecular Sequence Data Myocardium/metabolism Retina/embryology,metabolism Sequence Homology, Amino Acid Transcription Factors/genetics,physiology Xenopus Xenopus Proteins Zebrafish Zebrafish Proteins

Chemicals

Homeodomain Proteins IRX4 protein, human IRX5 protein, human Irx4 protein, Xenopus Transcription Factors Xenopus Proteins Zebrafish Proteins irx1a protein, zebrafish

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Garriock R J

Department of Cell Biology and Anatomy, University of Arizona Health Sciences Center, P.O. Box 245044, 1501 N. Campbell Avenue, Tucson, AZ 85724, USA.

Vokes S A

Small E M

Larson R

Krieg P A

Article Info

Journal

Development genes and evolution

Abbr.

Dev Genes Evol

ISSN

0949-944X

DOI

10.1007/s004270100147

Published

2001-05-00

Pages

257-60

Language

English

Region

Germany

NLM ID

9613264

Subset

Grants

NHLBI NIH HHS · HL63926 · United States

External Links

PubMed source DOI: 10.1007/s004270100147 View journal details

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Developmental expression of the Xenopus Iroquois-family homeobox genes, Irx4 and Irx5.

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