To B or not to B: TNF family signaling in lymphocytes.

Nature immunology ·Vol. 2 ·No. 7 ·2001-07-00 ·Pages 577-8

Siegel RM, Lenardo MJ

Abstract

BLyS and family are known to affect B cells in a positive fashion. Knock-outs of BLyS receptors indicate some new functions, including negative regulation by one BLyS receptor, TACI.

MeSH Terms

Animals Antigens, T-Independent/immunology B-Cell Activating Factor B-Cell Activation Factor Receptor B-Cell Maturation Antigen B-Lymphocytes/immunology Humans Lymphocytes/immunology Membrane Proteins/genetics,immunology,metabolism Neuropeptides/immunology Nuclear Proteins/immunology Receptors, Tumor Necrosis Factor/genetics,immunology Signal Transduction/immunology Tumor Necrosis Factor-alpha/genetics,immunology,metabolism

Chemicals

ANP32B protein, human Antigens, T-Independent B-Cell Activating Factor B-Cell Activation Factor Receptor B-Cell Maturation Antigen BLyS receptor Membrane Proteins Neuropeptides Nuclear Proteins Receptors, Tumor Necrosis Factor TNFRSF13C protein, human TNFRSF17 protein, human TNFSF13B protein, human Tumor Necrosis Factor-alpha

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Siegel R M

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA.

Lenardo M J

Article Info

Journal

Nature immunology

Abbr.

Nat Immunol

ISSN

1529-2908

DOI

10.1038/89715

Published

2001-07-00

Pages

577-8

Language

English

Region

United States

NLM ID

100941354

Subset

Corrections

CommentOn

PMID: 11429548

CommentOn

PMID: 11429549

External Links

PubMed source DOI: 10.1038/89715 View journal details

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To B or not to B: TNF family signaling in lymphocytes.

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