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PMID: 11391063 Published · ppublish English Journal Article Review

Alcohol and cancer.

Alcoholism, clinical and experimental research ·Vol. 25 ·No. 5 Suppl ISBRA ·2001-05-00 ·Pages 137S-143S

Seitz HK, Matsuzaki S, Yokoyama A, Homann N, Väkeväinen S, Wang XD

Abstract

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Helmut K. Seitz and Shohei Matsuzaki. The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanese alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-associated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde levels after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu Väkeväinen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (5) Alcohol and colorectal cancer, by Helmut K. Seitz.

MeSH Terms
Acetaldehyde/metabolism Alcohol Dehydrogenase/genetics,metabolism Alcoholism/genetics,metabolism Aldehyde Dehydrogenase/genetics,metabolism Aldehyde Dehydrogenase, Mitochondrial Animals Central Nervous System Depressants/metabolism,pharmacology Colorectal Neoplasms/etiology,metabolism Cytochrome P-450 CYP2E1/drug effects,metabolism Ethanol/metabolism,pharmacology Head and Neck Neoplasms/genetics,metabolism Humans Male Polymorphism, Genetic/genetics Risk Factors Saliva/drug effects,metabolism Vitamin A/metabolism
Chemicals
Central Nervous System Depressants Vitamin A Ethanol Alcohol Dehydrogenase Cytochrome P-450 CYP2E1 ALDH2 protein, human Aldehyde Dehydrogenase Aldehyde Dehydrogenase, Mitochondrial Acetaldehyde
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Seitz H K
Laboratory of Alcohol Research, Liver Disease and Nutrition, and Department of Medicine, Salem Medical Center, Heidelberg, Germany. Helmut_Karl.Seitz@urz.uni-heidelberg.de
Matsuzaki S
Yokoyama A
Homann N
Väkeväinen S
Wang X D
Article Info
Journal
Alcoholism, clinical and experimental research
Abbr.
Alcohol Clin Exp Res
ISSN
0145-6008
Published
2001-05-00
Pages
137S-143S
Language
English
Region
England
NLM ID
7707242
Subset
IM
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