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PMID: 11371628 Published · ppublish English Comment Journal Article

Glutamate antagonists: deadly liaisons with cancer.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 98 ·No. 11 ·2001-05-22 ·Pages 5947-8

Cavalheiro EA, Olney JW

Abstract

暂无摘要

MeSH Terms
Animals Anti-Anxiety Agents/pharmacology Antineoplastic Agents/pharmacology Benzodiazepines Cell Movement/drug effects Dizocilpine Maleate/pharmacology Drug Synergism Excitatory Amino Acid Antagonists/pharmacology Growth Inhibitors/pharmacology Humans Neoplasms/physiopathology Receptors, AMPA/antagonists & inhibitors Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors
Chemicals
Anti-Anxiety Agents Antineoplastic Agents Excitatory Amino Acid Antagonists Growth Inhibitors Receptors, AMPA Receptors, N-Methyl-D-Aspartate GYKI 52466 Benzodiazepines Dizocilpine Maleate
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Cavalheiro E A
Neurologia Experimental, Departamento de Neurologia e Neurocirurgia, Escola Paulista de Medicina/Universidade Federal de São Paulo, Rua Botucatu 862, 04023 São Paulo, SP, Brazil. esper.nexp@epm.br
Olney J W
References (24)
24 references, click to expand
  1. Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate.
    Science. 1969 May 9;164(3880):719-21 PMID: 5778021
  2. Excitatory amino acid transmitters.
    Annu Rev Pharmacol Toxicol. 1981;21:165-204 PMID: 6112965
  3. Bombesin, calcium homeostasis and tumour growth.
    Monaldi Arch Chest Dis. 1998 Aug;53(4):405-9 PMID: 9828595
  4. The toxic effect of sodium L-glutamate on the inner layers of the retina.
    AMA Arch Ophthalmol. 1957 Aug;58(2):193-201 PMID: 13443577
  5. Brain lesions in an infant rhesus monkey treated with monsodium glutamate.
    Science. 1969 Oct 17;166(3903):386-8 PMID: 5812037
  6. Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome.
    Science. 2000 Feb 11;287(5455):1056-60 PMID: 10669420
  7. Acidic amino acids with strong excitatory actions on mammalian neurones.
    J Physiol. 1963 Apr;166:1-14 PMID: 14024354
  8. Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils.
    Nature. 1995 Sep 7;377(6544):75-9 PMID: 7544874
  9. Diffusion across the nuclear envelope inhibited by depletion of the nuclear Ca2+ store.
    Science. 1995 Dec 15;270(5243):1835-8 PMID: 8525380
  10. Functional AMPA/kainate receptors in human embryonic and foetal central nervous system.
    J Chem Neuroanat. 1998 Mar;14(2):79-85 PMID: 9625352
  11. Synaptic activity mediates death of hypoxic neurons.
    Science. 1983 Apr 29;220(4596):536-7 PMID: 6836300
  12. Comparative aspects of the brain growth spurt.
    Early Hum Dev. 1979 Mar;3(1):79-83 PMID: 118862
  13. Inhibition and excitation due to gamma-aminobutyric acid in the central nervous system.
    Nature. 1958 Oct 18;182(4642):1076-7 PMID: 13590228
  14. Expression and regulation of kainate and AMPA receptors in uncommitted and committed neural progenitors.
    Neurochem Res. 1995 May;20(5):549-60 PMID: 7643960
  15. Calcium signaling.
    Cell. 1995 Jan 27;80(2):259-68 PMID: 7834745
  16. Glutamate signalling in non-neuronal tissues.
    Trends Pharmacol Sci. 2001 Apr;22(4):174-81 PMID: 11282417
  17. Glutamate antagonists limit tumor growth.
    Proc Natl Acad Sci U S A. 2001 May 22;98(11):6372-7 PMID: 11331750
  18. Role of 1,25-dihydroxyvitamin D3 and extracellular calcium in the regulation of proliferation in cultured SH-SY5Y human neuroblastoma cells.
    Neurochem Res. 1999 May;24(5):691-8 PMID: 10344599
  19. New order from neurological disorders.
    Nature. 1999 Jun 24;399(6738 Suppl):A3-5 PMID: 10392574
  20. Modulation of neuronal migration by NMDA receptors.
    Science. 1993 Apr 2;260(5104):95-7 PMID: 8096653
  21. Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system.
    Exp Brain Res. 1971;14(1):61-76 PMID: 5157537
  22. In vivo regulation of axon extension and pathfinding by growth-cone calcium transients.
    Nature. 1999 Jan 28;397(6717):350-5 PMID: 9950427
  23. Autoimmune encephalomyelitis ameliorated by AMPA antagonists.
    Nat Med. 2000 Jan;6(1):62-6 PMID: 10613825
  24. Modification of membrane currents in mouse neuroblastoma cells following infection with rabies virus.
    Br J Pharmacol. 1999 Apr;126(8):1691-8 PMID: 10372810
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.121179198
Email
esper.nexp@epm.br
Published
2001-05-22
Pages
5947-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC33400
Subset
IM
Corrections
CommentOn
PMID: 11331750
External Links
PubMed source DOI: 10.1073/pnas.121179198 PMC Full Text View journal details
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