A familial F/G translocation [t(p-; 22q+)] observed in three generations.

Clinical genetics ·Vol. 7 ·No. 2 ·1975-02-00 ·Pages 120-7

Cohen MM, Davidson RG, Brown JA

Abstract

A family is described in which a translocation between chromosomes 20 and 22 has been observed in three generations. Two first cousins with remarkably similar malformations and mental retardation have identical karyotypes which, after chromosome banding, were interpreted as partially trisomic for the short arm of chromosome No. 20.

MeSH Terms

Abnormalities, Multiple/genetics Adult Child Child, Preschool Chromosome Aberrations Chromosomes, Human, 21-22 and Y Face/abnormalities Female Hand Deformities, Congenital Humans Infant Intellectual Disability/genetics Karyotyping Male Pedigree Translocation, Genetic

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Cohen M M

Davidson R G

Brown J A

Article Info

Journal

Clinical genetics

Abbr.

Clin Genet

ISSN

0009-9163

DOI

10.1111/j.1399-0004.1975.tb00307.x

Published

1975-02-00

Pages

120-7

Language

English

Region

Denmark

NLM ID

0253664

Subset

External Links

PubMed source DOI: 10.1111/j.1399-0004.1975.tb00307.x View journal details

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A familial F/G translocation [t(p-; 22q+)] observed in three generations.

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