The process of epileptogenesis: a pathophysiological approach.

Current opinion in neurology ·Vol. 14 ·No. 2 ·2001-04-00 ·Pages 187-92

Dalby NO, Mody I

Abstract

Several recent advances have contributed to our understanding of the processes associated with mesial temporal lobe epilepsy in humans and in experimental animal models. Common pathological features between the human condition and the animal models may indicate a fundamental involvement of the given pathology in the process of epileptogenesis.

MeSH Terms

Animals Disease Models, Animal Epilepsy, Temporal Lobe/etiology,pathology,physiopathology Glutamic Acid/metabolism Hippocampus/metabolism,pathology,physiopathology Humans Interneurons/metabolism,pathology Mossy Fibers, Hippocampal/metabolism,pathology Neural Inhibition/physiology Neuronal Plasticity/physiology gamma-Aminobutyric Acid/metabolism

Chemicals

Glutamic Acid gamma-Aminobutyric Acid

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Dalby N O

Department of Neurology, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, California 90095-1769, USA.

Mody I

Article Info

Journal

Current opinion in neurology

Abbr.

Curr Opin Neurol

ISSN

1350-7540

DOI

10.1097/00019052-200104000-00009

Published

2001-04-00

Pages

187-92

Language

English

Region

England

NLM ID

9319162

Subset

External Links

PubMed source DOI: 10.1097/00019052-200104000-00009 View journal details

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