Slow axonal transport: stop and go traffic in the axon.

Nature reviews. Molecular cell biology ·Vol. 1 ·No. 2 ·2000-11-00 ·Pages 153-6

Brown A

Abstract

Efforts to observe the slow axonal transport of cytoskeletal polymers during the past decade have yielded conflicting results, and this has generated considerable controversy. The movement of neurofilaments has now been seen, and it is rapid, infrequent and highly asynchronous. This motile behaviour could explain why slow axonal transport has eluded observation for so long.

MeSH Terms

Animals Axonal Transport/physiology Axons/physiology Cytoskeletal Proteins/metabolism Cytoskeleton/physiology Models, Neurological Neurons/physiology

Chemicals

Cytoskeletal Proteins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Brown A

Neuroscience Program, Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA. browna1@ohio.edu

Article Info

Journal

Nature reviews. Molecular cell biology

Abbr.

Nat Rev Mol Cell Biol

ISSN

1471-0072

DOI

10.1038/35040102

browna1@ohio.edu

Published

2000-11-00

Pages

153-6

Language

English

Region

England

NLM ID

100962782

Subset

Grants

NINDS NIH HHS · R01 NS038526 · United States

NINDS NIH HHS · R01 NS038526-02 · United States

External Links

PubMed source DOI: 10.1038/35040102 View journal details

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Slow axonal transport: stop and go traffic in the axon.

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