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题目:: Generation and maintenance of memory T cells.
作者:: Sprent(J),Surh(C D)
状态:: 发布时间2001-03-06 , 更新时间 2007-11-14
期刊:: Curr Opin Immunol
摘要:: Typical immune responses lead to the prominent clonal expansion of antigen-specific T cells followed by their differentiation into effector cells. Most effector cells die at the end of the immune response but some of the responding cells survive and form long-lived memory cells. The factors controlling the formation and survival of memory T cells are discussed. Recent evidence suggests that T memory cells arise from a subset of effector cells. The longevity of T memory cells may require continuous contact with cytokines, notably IL-15 for CD8(+) cells.
语言:: eng
DOI:

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