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PMID: 11178275 Published · ppublish English Letter Research Support, Non-U.S. Gov't

Genome sequences and great expectations.

Genome biology ·Vol. 2 ·No. 1 ·2001-00-00 ·Pages INTERACTIONS0001

Iliopoulos I, Tsoka S, Andrade MA, Janssen P, Audit B, Tramontano A, Valencia A, Leroy C, Sander C, Ouzounis CA

Abstract

To assess how automatic function assignment will contribute to genome annotation in the next five years, we have performed an analysis of 31 available genome sequences. An emerging pattern is that function can be predicted for almost two-thirds of the 73,500 genes that were analyzed. Despite progress in computational biology, there will always be a great need for large-scale experimental determination of protein function.

MeSH Terms
Animals Genome Genome, Human Genomics/methods,trends Humans Proteome Sequence Analysis, DNA/methods,trends
Chemicals
Proteome
Authors & Affiliations
10 authors, click to expand affiliations / ORCID
Iliopoulos I
Computational Genomics Group, Research Programme, The European Bioinformatics Institute, EMBL Cambridge Outstation, Cambridge, CB10 1SD, UK.
Tsoka S
Andrade M A
Janssen P
Audit B
Tramontano A
Valencia A
Leroy C
Sander C
Ouzounis C A
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Article Info
Journal
Genome biology
Abbr.
Genome Biol
ISSN
1474-760X
DOI
10.1186/gb-2000-2-1-interactions0001
Published
2001-00-00
Epub
2000-00-29
Pages
INTERACTIONS0001
Language
English
Region
England
NLM ID
100960660
PMCID
PMC150431
Subset
IM
External Links
PubMed source DOI: 10.1186/gb-2000-2-1-interactions0001 PMC Full Text View journal details
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