Biosynthesis of the methanogenic cofactors.

Vitamins and hormones ·Vol. 61 ·2001-00-00 ·Pages 299-337

White RH

Abstract

Our current knowledge of the pathways and genes involved in the biosynthesis of the methanogenic coenzymes methanopterin, coenzyme B, methanofuran, coenzyme F420, and coenzyme M is presented. Proposed reaction mechanisms for several of the novel reactions involved in the pathways are presented.

MeSH Terms

Coenzymes/biosynthesis,metabolism Furans/metabolism Gene Expression Regulation, Archaeal Mesna/metabolism Methanococcus/genetics,metabolism Molecular Structure Phosphothreonine/analogs & derivatives,metabolism Pterins/metabolism Riboflavin/analogs & derivatives,biosynthesis

Chemicals

Coenzymes Furans Pterins 7-mercaptoheptanoylthreonine phosphate Phosphothreonine coenzyme F420 methanopterin carbon dioxide reduction factor Mesna Riboflavin

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

White R H

Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

Article Info

Journal

Vitamins and hormones

Abbr.

Vitam Horm

ISSN

0083-6729

DOI

10.1016/s0083-6729(01)61010-0

Published

2001-00-00

Pages

299-337

Language

English

Region

United States

NLM ID

0413601

Subset

External Links

PubMed source DOI: 10.1016/s0083-6729(01)61010-0 View journal details

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Biosynthesis of the methanogenic cofactors.

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