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Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation.
J Exp Med. 1998 Nov 2;188(9):1739-50
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Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts.
Arthritis Rheum. 1998 Nov;41(11):1987-94
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NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint.
Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13859-64
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J Immunol. 1999 Dec 15;163(12):6827-33
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Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy.
Arthritis Rheum. 1999 Dec;42(12):2532-42
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A functional role of I kappa B-epsilon in endothelial cell activation.
J Immunol. 2000 Mar 15;164(6):3316-22
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Expression and activation of NF-kappa B in the antrum of the human stomach.
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Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3.
Arthritis Rheum. 2000 Apr;43(4):801-11
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NAK is an IkappaB kinase-activating kinase.
Nature. 2000 Apr 13;404(6779):778-82
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High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation.
Nat Med. 2000 May;6(5):573-7
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Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer.
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NF-kappaB in neuronal plasticity and neurodegenerative disorders.
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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.
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Selective inhibition of E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 expression by inhibitors of I kappa B-alpha phosphorylation.
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Biochim Biophys Acta. 1996 Jun 7;1316(2):132-8
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Annu Rev Immunol. 1996;14:649-83
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Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice.
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The effect of dexamethasone on the expression of activated NF-kappa B in adjuvant arthritis.
Clin Immunol Immunopathol. 1997 May;83(2):173-8
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A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription.
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Requirement for NF-kappaB in osteoclast and B-cell development.
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Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1.
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New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases.
Clin Chem. 1999 Jan;45(1):7-17
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Cytokine gene transcription by NF-kappa B family members in patients with inflammatory bowel disease.
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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase.
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Signal transduction and transcription factors in rheumatic disease.
Arthritis Rheum. 1999 Apr;42(4):609-21
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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
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NF-kappa B regulation by I kappa B kinase in primary fibroblast-like synoviocytes.
J Immunol. 1999 Jul 1;163(1):427-33
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Essential role of T cell NF-kappa B activation in collagen-induced arthritis.
J Immunol. 1999 Aug 1;163(3):1577-83
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IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases.
Int Immunol. 1999 Aug;11(8):1357-62
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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling.
Nature. 1999 Sep 2;401(6748):86-90
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Increased nuclear factor-kappaB activation in colitis of interleukin-2-deficient mice.
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Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate.
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