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PMID: 1111857 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Protective effect of immunoglobulins in serum and milk of sows exposed to transmissible gastroenteritis virus.

Canadian journal of comparative medicine : Revue canadienne de medecine comparee ·Vol. 39 ·No. 1 ·1975-01-00 ·Pages 41-5

Abou-Youssef MH, Ristic M

Abstract

Experimental exposure of susceptible pregnant sows by various routes to the gut-origin transmissible gastroenteritis virus stimulated production of milk and serum antibodies. These antibodies neutralized the cytopathic effect of transmissible gastroenteritis virus propagated in cell culture. This in vitro neutralizing antibody resided in the IgG and IgA immunoglobulin classes. On the other hand, protection for baby pigs resided in the IgA class of milk immunoglobulin of sows exposed orally or intramammarily but not of sows exposed intramuscularly to the virus.

MeSH Terms

Animals Animals, Newborn Antibodies, Viral/analysis Chromatography, DEAE-Cellulose Chromatography, Gel Coronaviridae/immunology Dose-Response Relationship, Drug Female Gastroenteritis, Transmissible, of Swine/immunology Immunization, Passive Immunoglobulin M/analysis Immunoglobulins Milk/immunology Neutralization Tests Pregnancy Swine

Chemicals

Antibodies, Viral Immunoglobulin M Immunoglobulins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Abou-Youssef M H

Ristic M

References (12)

12 references, click to expand

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Article Info

Journal

Canadian journal of comparative medicine : Revue canadienne de medecine comparee

Abbr.

Can J Comp Med

ISSN

0008-4050

Published

1975-01-00

Pages

41-5

Language

English

Region

Canada

NLM ID

0151747

PMCID

PMC1277412

Subset

External Links

PubMed source PMC Full Text

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Protective effect of immunoglobulins in serum and milk of sows exposed to transmissible gastroenteritis virus.

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