Home LiteratureArticle Details

PMID: 11108642 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Use of classification trees for association studies.

Genetic epidemiology ·Vol. 19 ·No. 4 ·2000-12-00 ·Pages 323-32

Zhang H, Bonney G

Abstract

We propose the use of classification trees for association studies. This approach is applied to a data set from Genetic Analysis Workshop 9 (GAW9), and our analysis precisely identified two disease alleles. Our purpose is to demonstrate the great potential of tree-based analyses for genetic studies, and discuss some issues that warrant further investigation.

MeSH Terms

Alleles Family Health Genetic Linkage Genetic Markers Genetic Predisposition to Disease Genome, Human Humans Models, Genetic Models, Statistical Molecular Epidemiology/methods Polymorphism, Genetic

Chemicals

Genetic Markers

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Zhang H

Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520-8034, USA. heping.zhang@yale.edu

Bonney G

Article Info

Journal

Genetic epidemiology

Abbr.

Genet Epidemiol

ISSN

0741-0395

DOI

10.1002/1098-2272(200012)19:4<323::AID-GEPI4>3.0.CO;2-5

heping.zhang@yale.edu

Published

2000-12-00

Pages

323-32

Language

English

Region

United States

NLM ID

8411723

Subset

Grants

NIA NIH HHS · AG16996 · United States

NIGMS NIH HHS · GM31575 · United States

NICHD NIH HHS · HD30712 · United States

External Links

PubMed source DOI: 10.1002/1098-2272(200012)19:4<323::AID-GEPI4>3.0.CO;2-5 View journal details

Analysis Services

Use of classification trees for association studies.

Contact

WeChat Official Account