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PMID: 11076721 Published · ppublish English Journal Article

Risk factors for otitis media and carriage of multiple strains of Haemophilus influenzae and Streptococcus pneumoniae.

Emerging infectious diseases ·Vol. 6 ·No. 6 ·2000-00-00 ·Pages 622-30

St Sauver J, Marrs CF, Foxman B, Somsel P, Madera R, Gilsdorf JR

Abstract

We studied genetic diversity in Streptococcus pneumoniae and Haemophilus influenzae in throat culture isolates from 38 children attending two day-care centers in Michigan. Culture specimens were collected weekly; 184 S. pneumoniae and 418 H. influenzae were isolated from the cultures. Pulsed-field gel electrophoresis identified 29 patterns among the S. pneumoniae isolates and 87 among the H. influenzae isolates. Of the cultures, 5% contained multiple genetic types of S. pneumoniae, and 43% contained multiple types of H. influenzae. Carriage of multiple H. influenzae isolates, which was associated with exposure to smoking, history of allergies, and age 36 to 47 months, may increase risk for otitis media in children.

MeSH Terms
Carrier State Child Child, Preschool Electrophoresis, Gel, Pulsed-Field Female Genetic Variation Haemophilus influenzae/genetics,isolation & purification Humans Infant Infant, Newborn Male Otitis Media/etiology Pharynx/microbiology Risk Factors Streptococcus pneumoniae/genetics,isolation & purification
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
St Sauver J
University of Michigan, Ann Arbor, Michigan, USA.
Marrs C F
Foxman B
Somsel P
Madera R
Gilsdorf J R
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Article Info
Journal
Emerging infectious diseases
Abbr.
Emerg Infect Dis
ISSN
1080-6040
DOI
10.3201/eid0606.000611
Published
2000-00-00
Pages
622-30
Language
English
Region
United States
NLM ID
9508155
PMCID
PMC2640914
Subset
IM
External Links
PubMed source DOI: 10.3201/eid0606.000611 PMC Full Text View journal details
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