New antibacterial metabolites from the cyanobacterium Nostoc commune(EAWAG 122b).

Journal of natural products ·Vol. 63 ·No. 9 ·2000-09-00 ·Pages 1283-5

Jaki B, Heilmann J, Sticher O

Abstract

Two new compounds, a diterpenoid and an anthraquinone, as well as an indane derivative, which is reported as a natural product for the first time, have been isolated from the cells of the cultured cyanobacterium Nostoc commune (EAWAG 122b) by means of bioguided isolation. The structures were determined by spectroscopic methods, mainly NMR, infrared spectroscopy, and mass spectrometry. All isolates exhibit antibacterial activity.

MeSH Terms

Anthraquinones/chemistry,isolation & purification,metabolism,pharmacology Anti-Bacterial Agents/chemistry,isolation & purification,metabolism,pharmacology Bacillus cereus/drug effects Cyanobacteria/metabolism Diterpenes/chemistry,isolation & purification,metabolism,pharmacology Microbial Sensitivity Tests Molecular Structure Spectrum Analysis Staphylococcus epidermidis/drug effects

Chemicals

Anthraquinones Anti-Bacterial Agents Diterpenes

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Jaki B

Department of Applied BioSiences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8057 Zürich, Switzerland.

Heilmann J

Sticher O

Article Info

Journal

Journal of natural products

Abbr.

J Nat Prod

ISSN

0163-3864

DOI

10.1021/np000033s

Published

2000-09-00

Pages

1283-5

Language

English

Region

United States

NLM ID

7906882

Subset

External Links

PubMed source DOI: 10.1021/np000033s View journal details

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New antibacterial metabolites from the cyanobacterium Nostoc commune(EAWAG 122b).

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