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PMID: 10992555 Published · ppublish English Journal Article

Lipoxins and other arachidonate derived mediators in bronchial asthma.

Thorax ·Vol. 55 Suppl 2 ·2000-10-00 ·Pages S38-41

Chavis C, Vachier I, Godard P, Bousquet J, Chanez P

Abstract

暂无摘要

MeSH Terms
Arachidonic Acid/metabolism Asthma/metabolism Calcimycin/pharmacology Cell Culture Techniques Eicosanoids/biosynthesis Glucocorticoids/pharmacology Humans Hydroxyeicosatetraenoic Acids/pharmacology Ionophores/pharmacology Macrophages, Alveolar/drug effects,metabolism Monocytes/drug effects,metabolism Neutrophils/drug effects,metabolism
Chemicals
Eicosanoids Glucocorticoids Hydroxyeicosatetraenoic Acids Ionophores Arachidonic Acid Calcimycin 15-hydroxy-5,8,11,13-eicosatetraenoic acid
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Chavis C
Inserm U454, CHU de Montpellier, Hôpital Arnaud de Villeneuve, 34295 Montpellier, France. cchavis@montp.inserm.fr
Vachier I
Godard P
Bousquet J
Chanez P
References (33)
33 references, click to expand
  1. Lymphocyte subpopulations in bronchoalveolar lavages of patients with sarcoidosis and hypersensitivity pneumonitis.
    Chest. 1981 Oct;80(4):447-52 PMID: 6974088
  2. Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain.
    J Neurochem. 1999 Aug;73(2):693-9 PMID: 10428066
  3. Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea.
    Proc Natl Acad Sci U S A. 1985 Jul;82(14):4633-7 PMID: 3927287
  4. On the stereochemistry and biosynthesis of lipoxin B.
    Proc Natl Acad Sci U S A. 1986 Apr;83(7):1983-7 PMID: 3083410
  5. Formation of lipoxins by alveolar macrophages.
    Biochem Biophys Res Commun. 1988 Jan 29;150(2):870-6 PMID: 3124841
  6. Release of leukotrienes in patients with bronchial asthma.
    J Allergy Clin Immunol. 1988 Apr;81(4):711-7 PMID: 3356850
  7. Leukotriene B4 as a mediator of early and late reactions to antigen in humans: the effect of systemic glucocorticoid treatment in vivo.
    J Allergy Clin Immunol. 1989 Mar;83(3):634-42 PMID: 2466880
  8. On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE.
    Biochim Biophys Acta. 1989 Aug 8;1004(2):158-68 PMID: 2546590
  9. Biochemistry of the lipoxygenase pathways in neutrophils.
    Can J Physiol Pharmacol. 1989 Aug;67(8):936-42 PMID: 2513107
  10. Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases.
    Am Rev Respir Dis. 1990 Jun;141(6):1453-8 PMID: 2161628
  11. Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge.
    Am Rev Respir Dis. 1990 Jul;142(1):112-9 PMID: 2195930
  12. Lipoxin formation in human nasal polyps and bronchial tissue.
    FEBS Lett. 1990 Oct 15;272(1-2):25-8 PMID: 2172016
  13. Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils.
    J Exp Med. 1990 Nov 1;172(5):1451-7 PMID: 2172436
  14. 15(S)-hydroxyeicosatetraenoic acid is the major arachidonic acid metabolite in human bronchi: association with airway epithelium.
    Arch Biochem Biophys. 1990 Nov 1;282(2):254-62 PMID: 2122804
  15. Sulfidopeptide leukotrienes contribute to human alveolar macrophage activation in asthma.
    Prostaglandins Leukot Essent Fatty Acids. 1991 Feb;42(2):95-100 PMID: 1850529
  16. Characterization of lipoxins by combined gas chromatography and electron-capture negative ion chemical ionization mass spectrometry: formation of lipoxin A4 by stimulated human whole blood.
    Biol Mass Spectrom. 1991 Feb;20(2):45-52 PMID: 1883860
  17. Leukotrienes.
    Allergy Proc. 1991 May-Jun;12(3):139-42 PMID: 1654285
  18. Formation and proliferative effects of lipoxins in human bone marrow.
    Biochem Biophys Res Commun. 1991 Oct 15;180(1):255-61 PMID: 1930222
  19. 15-hydroxyeicosatetraenoic acid synthesis from exogenous arachidonate by bronchial mucosa.
    J Lipid Mediat. 1990 Sep-Oct;2(5):263-9 PMID: 2133271
  20. The effects of lipoxin A4 on airway responses in asthmatic subjects.
    Am Rev Respir Dis. 1992 Jun;145(6):1281-4 PMID: 1595991
  21. The effects of beta 2-adrenoceptor agonists and a corticosteroid, budesonide, on the secretion of inflammatory mediators from monocytes.
    Br J Pharmacol. 1992 Sep;107(1):156-60 PMID: 1358381
  22. Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells.
    Eicosanoids. 1992;5(3-4):203-11 PMID: 1337977
  23. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins.
    J Clin Invest. 1993 Sep;92(3):1572-9 PMID: 8376607
  24. Interleukin-1 increases 15-hydroxyeicosatetraenoic acid formation in cultured human endothelial cells.
    Biochim Biophys Acta. 1993 Sep 29;1170(1):17-24 PMID: 7691182
  25. Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids.
    J Appl Physiol (1985). 1993 Dec;75(6):2368-75 PMID: 8125852
  26. Conversion of endogenous arachidonic acid to 5,15-diHETE and lipoxins by polymorphonuclear cells from patients with rheumatoid arthritis.
    Inflamm Res. 1995 Mar;44(3):121-4 PMID: 7552576
  27. 5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors.
    J Exp Med. 1996 Apr 1;183(4):1633-43 PMID: 8666921
  28. Dexamethasone increases expression of 5-lipoxygenase and its activating protein in human monocytes and THP-1 cells.
    Eur J Biochem. 1997 May 15;246(1):112-8 PMID: 9210472
  29. Eicosanoid production from porcine neutrophils and platelets: differential production with various agonists.
    Am J Physiol. 1997 Jun;272(6 Pt 1):C1821-8 PMID: 9227410
  30. Generation of eicosanoids from 15(S)-hydroxyeicosatetraenoic acid in blood monocytes from steroid-dependent asthmatic patients.
    Biochem Pharmacol. 1998 Aug 15;56(4):535-41 PMID: 9763231
  31. Regulation of leukocyte trafficking by lipoxins.
    Clin Chem Lab Med. 1999 Mar;37(3):293-7 PMID: 10353475
  32. Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators.
    Clin Chem Lab Med. 1999 Mar;37(3):299-309 PMID: 10353476
  33. Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes.
    Biochem Biophys Res Commun. 1984 Feb 14;118(3):943-9 PMID: 6422933
Article Info
Journal
Thorax
Abbr.
Thorax
ISSN
0040-6376
DOI
10.1136/thorax.55.suppl_2.s38
Email
cchavis@montp.inserm.fr
Published
2000-10-00
Pages
S38-41
Language
English
Region
England
NLM ID
0417353
PMCID
PMC1765959
Subset
IM
External Links
PubMed source DOI: 10.1136/thorax.55.suppl_2.s38 PMC Full Text View journal details
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