Abstract
The enzyme-linked immunosorbent assay (ELISA) technique, using an ultrasonicate of Treponema pallidum as antigen, has been evaluated as a serological test for syphilis. It is concluded that the test is simple, reliable, and relatively quick and that its sensitivity in all stages of syphilis is equal to the FTAABS test. Because its specificity is probably also high, ELISA might be used in future as a first-line screening test for the serodiagnosis of syphilis.
MeSH Terms
Adsorption
Alkaline Phosphatase
Antibodies, Anti-Idiotypic
Complement Fixation Tests
Fluorescent Antibody Technique
Humans
Immunoglobulins
Syphilis Serodiagnosis/methods
Treponema Immobilization Test
Chemicals
Antibodies, Anti-Idiotypic
Immunoglobulins
Alkaline Phosphatase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Veldkamp J
Visser A M
References (6)
6 references, click to expand
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