Effects of the antibiotics netropsin and distamycin A on the structure and function of nucleic acids.

Animals Anti-Bacterial Agents/pharmacology Binding Sites Chromatin/metabolism,ultrastructure Circular Dichroism DNA/metabolism DNA Nucleotidyltransferases/antagonists & inhibitors DNA-Directed RNA Polymerases/antagonists & inhibitors Distamycins/pharmacology Guanidines/pharmacology Nucleic Acid Conformation Nucleic Acid Denaturation Oligopeptides/pharmacology Polynucleotides Protein Binding Pyrroles/metabolism RNA/metabolism Spectrophotometry, Ultraviolet Structure-Activity Relationship Templates, Genetic Thymus Gland

Anti-Bacterial Agents Chromatin Distamycins Guanidines Oligopeptides Polynucleotides Pyrroles RNA DNA DNA Nucleotidyltransferases DNA-Directed RNA Polymerases