Specific inhibition of ribosomal RNA synthesis in vitro by guanosine 3' diphosphate, 5' diphosphate.

DNA, Bacterial/metabolism DNA-Directed RNA Polymerases/metabolism Depression, Chemical Escherichia coli/drug effects,metabolism Guanine Nucleotides/pharmacology In Vitro Techniques Nucleic Acid Hybridization Phosphorus Radioisotopes Proteus/metabolism RNA, Bacterial/biosynthesis RNA, Ribosomal/biosynthesis Templates, Genetic Tritium

DNA, Bacterial Guanine Nucleotides Phosphorus Radioisotopes RNA, Bacterial RNA, Ribosomal Tritium DNA-Directed RNA Polymerases