Duplication-deficiency of the short arm of chromosome 8 following artificial insemination.

Annales de genetique ·Vol. 19 ·No. 4 ·1976-12-00 ·Pages 241-7

Weleber RG, Verma RS, Kimberling WJ, Fieger HG, lubs HA

Abstract

A chromosomally abnormal child with psychomotor retardation and multiple anomalies, including agenesis of the corpus callosum and cleft palate, was born following artificial insemination by donor. Chromosomal and conventional markers were used to ascertain paternity. Various banding techniques were employed to identify the origin of the extra chromosomal material as most likely a duplication-deficiency of the short arm of chromosome No. 8.

Keywords

Artificial Insemination Case Studies Chromosome Abnormalities Congenital Abnormalities Diseases Neonatal Diseases And Abnormalities Reproduction Reproductive Technologies Research Methodology Studies

MeSH Terms

Abnormalities, Multiple/genetics Chromosome Aberrations/genetics Chromosome Disorders Chromosomes, Human, 6-12 and X Dermatoglyphics Female Humans Infant Infant, Newborn Insemination, Artificial Intellectual Disability/genetics Karyotyping

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Weleber R G

Verma R S

Kimberling W J

Fieger H G

lubs H A

Other Abstracts

eng

A case study of a chromosomally abnormal child, conceived through artificial insemination, with psychomotor retardation and multiple anomalies, including agenesis of the corpus callosum and cleft palate, is reported. Paternity was established through chromosomal and conventional markers. Various banding techniques were used to determine the origin of the extra chromosome. It is likely that the extra chromosomal material was the result of a duplication-deficiency of the short arm of chromosome No. 8.

Article Info

Journal

Annales de genetique

Abbr.

Ann Genet

ISSN

0003-3995

Published

1976-12-00

Pages

241-7

Language

English

Region

Netherlands

NLM ID

0370562

Subset

External Links

PubMed source

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Duplication-deficiency of the short arm of chromosome 8 following artificial insemination.

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