[Adhesion molecules as the strategic goal of immunotherapy].
作者:
Horvathova(M),Ferencik(M)
状态:
发布时间2000-07-20
, 更新时间 2016-10-26
期刊:
Bratisl Lek Listy
摘要:
Adhesion molecules are cell surface glycoproteins involved in cell-cell and cell-matrix interactions. They play a central role in leukocyte adhesion to endothelium, transmigration, binding to target cells and cytotoxicity. Many pathological processes underlie abnormal cell-cell interactions in the organism. The adhesion molecules are critical for the communication mechanism between cells in inflammatory and immunologic response. The control of cell-cell adhesive interactions, i.e. modulation of adhesion molecules, is an important strategy for anti-inflammatory therapy. (Ref. 65.)