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题目:: The Lynch Syndrome: Melding Natural History and Molecular Genetics to Genetic Counseling and Cancer Control.
作者:: Lynch,Lynch
状态:: 发布时间2000-05-24 , 更新时间 2000-05-24
期刊:: Cancer Control
摘要:: Hereditary nonpolyposis colorectal cancer (HNPCC), also referred to as Lynch syndromes I and II, is an autosomal, dominantly inherited disorder that accounts for approximately 5% of all colorectal cancers. While colorectal cancer is the most frequently occurring malignancy in HNPCC, other types of cancer occur with increased statistical significance. A better understanding of its natural history, particularly early age of onset and the pattern of multiple primary cancer excess, is essential for the diagnosis and management of HNPCC.
语言:: eng
DOI:

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