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PMID: 1080496 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Determination of the von Willebrand's disease antigen (factor VIII-related antigen) in plasma by quantitative immunoelectrophoresis.

The Journal of laboratory and clinical medicine ·Vol. 86 ·No. 1 ·1975-07-00 ·Pages 152-9

Zimmerman TS, Hoyer LW, Dickson L, Edgington TS

Abstract

Measurement of the von Willebrand's disease antigen (factor viii-related antigen) has become an increasingly useful tool in the differential diagnosis of those disorders of hemostasis characterized by an abnormality of factor viii procoagulant activity. Optimal conditions for assay of the von Willebrand's disease antigen in plasma by the quantitive immunoelectrophoretic technique are described. Potential sources ofsystematic error have been evaluated and a dilution effect has been identified.

MeSH Terms
Animals Antigens/analysis Chromatography Diagnosis, Differential Factor VIII/immunology Humans Immunoelectrophoresis/methods Rabbits Serum Globulins/analysis von Willebrand Diseases/immunology
Chemicals
Antigens Serum Globulins Factor VIII
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Zimmerman T S
Hoyer L W
Dickson L
Edgington T S
Article Info
Journal
The Journal of laboratory and clinical medicine
Abbr.
J Lab Clin Med
ISSN
0022-2143
Published
1975-07-00
Pages
152-9
Language
English
Region
United States
NLM ID
0375375
Subset
IM
External Links
PubMed source
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