Transport of nucleosides in Bacillus subtilis: characteristics of cytidine-uptake.

Nucleic acids research ·Vol. 1 ·No. 4 ·1974-04-00 ·Pages 629-37

Kloudová A, Fucik V

Abstract

In Bacillus subtilis SMYW cytidine and uridine are transported by a common system. Transport of these substances requires metabolic energy. After 60 sec of (3)II-cytidine-uptake practically all accumulated radioactivity was found in phosphorylated products. Addition of ribonucleosides with inhibitory effect upon cytidine-uptake resulted in competitive type of inhibition while interference with deoxyribonucleosides was of hyperbolic competitive type. Adenosine possesses a high affinity to cytidine-transporting site but requires different system(s) for its own transport. Guanosine, adenine, cytosine and 5-nucleotides do not interfere with cytidine-uptake.

MeSH Terms

Bacillus subtilis/metabolism Biological Transport, Active Cytidine/metabolism Kinetics Nucleosides/metabolism

Chemicals

Nucleosides Cytidine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kloudová A

Fucik V

References (14)

14 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/1.4.629

Published

1974-04-00

Pages

629-37

Language

English

Region

England

NLM ID

0411011

PMCID

PMC343361

Subset

External Links

PubMed source DOI: 10.1093/nar/1.4.629 PMC Full Text View journal details

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Transport of nucleosides in Bacillus subtilis: characteristics of cytidine-uptake.

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