The ins and outs of EBV infection.

Trends in microbiology ·Vol. 8 ·No. 4 ·2000-04-00 ·Pages 185-9

Faulkner GC, Krajewski AS, Crawford DH

Abstract

Epstein-Barr virus (EBV) infects almost the entire adult population of the world. The success of this virus appears to be based on its ability to infect the B cell, rather than any other cell type. We review EBV B-cell tropism, and discuss the mechanisms by which the virus may gain access to, and egress from, B cells in the normal host.

MeSH Terms

B-Lymphocytes/immunology,pathology,virology Epithelial Cells/virology Epstein-Barr Virus Infections/immunology,pathology,virology Herpesvirus 4, Human/immunology,pathogenicity,physiology Humans Organ Specificity Saliva/virology Virus Replication

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Faulkner G C

Depts of Medical Microbiology and Pathology, University of Edinburgh Medical School, Teviot Place, Edinburgh, UK EH8 9AG.

Krajewski A S

Crawford D H

Article Info

Journal

Trends in microbiology

Abbr.

Trends Microbiol

ISSN

0966-842X

DOI

10.1016/s0966-842x(00)01742-x

Published

2000-04-00

Pages

185-9

Language

English

Region

England

NLM ID

9310916

Subset

External Links

PubMed source DOI: 10.1016/s0966-842x(00)01742-x View journal details

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