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题目:: Cell-anchorage, cell cytoskeleton, and Rho-GTPase family in regulation of cell cycle progression.
作者:: Tatsuno(I),Hirai(A),Saito(Y)
状态:: 发布时间2000-06-12 , 更新时间 2009-11-19
期刊:: Prog Cell Cycle Res
摘要:: It has been well known that cell-anchorage and the cell cytoskeleton are deeply involved in the regulation of cell proliferation and cell cycle. However, the precise molecular mechanism involved in cell-anchorage and the cell cytoskeleton have remained be to elucidated. The recent great volume of information regarding cell cycle regulators such as cyclin, cyclin-dependent kinases (CDKs) and CDK inhibitors (CKI) has facilitated the understanding of the cell cycle in mammalian cells. In this review, we will focus on these cell cycle regulators to discuss the regulation of cell proliferation controlled by cell-anchorage and the cytoskeleton, and especially the roles of Rho family GTPases.
语言:: eng
DOI:

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