Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans.

Amyloid beta-Protein Precursor/metabolism Animals Bacteria/enzymology CCAAT-Enhancer-Binding Proteins DNA-Binding Proteins/metabolism Endopeptidases/metabolism Endoribonucleases Humans Membrane Proteins/metabolism Nuclear Proteins/metabolism Protein Folding Protein Serine-Threonine Kinases/metabolism Sterol Regulatory Element Binding Protein 1 Transcription Factors

Amyloid beta-Protein Precursor CCAAT-Enhancer-Binding Proteins DNA-Binding Proteins Membrane Proteins Nuclear Proteins SREBF1 protein, human Sterol Regulatory Element Binding Protein 1 Transcription Factors ERN2 protein, human Protein Serine-Threonine Kinases Endoribonucleases Endopeptidases