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PMID: 10691739 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A Krüppel-like zinc finger protein is involved in nitrogen-fixing root nodule organogenesis.

Genes & development ·Vol. 14 ·No. 4 ·2000-02-15 ·Pages 475-82

Frugier F, Poirier S, Satiat-Jeunemaître B, Kondorosi A, Crespi M

Abstract

Mechanisms regulating plant host differentiation of the nitrogen-fixing root nodules remain mostly unknown. Sinorhizobium meliloti induces this process in Medicago sativa in which the Mszpt2-1 gene is expressed in vascular bundles of roots and nodules. This gene codes for a Krüppel-like zinc finger protein, a class of transcription factors involved in many animal developmental processes. Expression of Mszpt2-1 in yeast cells conferred osmotic tolerance. Antisense plants grew normally but developed nonfunctional nodules, in which differentiation of the nitrogen-fixing zone and bacterial invasion were arrested. Hence, a vascular bundle-associated Krüppel-like gene is required for the formation of the central nitrogen-fixing zone of the root nodule.

MeSH Terms
Amino Acid Sequence DNA, Antisense/genetics DNA, Plant/genetics Gene Expression Regulation, Plant Genes, Plant In Situ Hybridization Medicago sativa/microbiology,physiology,ultrastructure Molecular Sequence Data Nitrogen Fixation/genetics,physiology Plant Proteins/genetics,physiology Plant Roots/growth & development,microbiology Plants, Genetically Modified Recombinant Fusion Proteins/biosynthesis,genetics Sinorhizobium meliloti/physiology Transcription Factors/biosynthesis,genetics,physiology Zinc Fingers/genetics,physiology
Chemicals
DNA, Antisense DNA, Plant Mszpt2-1 protein, Medicago sativa Plant Proteins Recombinant Fusion Proteins Transcription Factors
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Frugier F
Institut des Sciences Végétales, Centre National de la Recherche Scientifique (CNRS), F-91198 Gif-sur-Yvette Cedex, France.
Poirier S
Satiat-Jeunemaître B
Kondorosi A
Crespi M
References (30)
30 references, click to expand
  1. Correlation between ultrastructural differentiation of bacteroids and nitrogen fixation in alfalfa nodules.
    J Bacteriol. 1990 Aug;172(8):4295-306 PMID: 2376562
  2. Alteration of enod40 expression modifies medicago truncatula root nodule development induced by sinorhizobium meliloti
    Plant Cell. 1999 Oct;11(10):1953-66 PMID: 10521525
  3. Identification of protein coding regions by database similarity search.
    Nat Genet. 1993 Mar;3(3):266-72 PMID: 8485583
  4. Identification of novel putative regulatory genes induced during alfalfa nodule development with a cold-plaque screening procedure.
    Mol Plant Microbe Interact. 1998 May;11(5):358-66 PMID: 9574504
  5. An alfalfa cDNA encodes a protein with homology to translationally controlled human tumor protein.
    Plant Mol Biol. 1992 Jun;19(3):501-3 PMID: 1623194
  6. Genomic sequencing.
    Proc Natl Acad Sci U S A. 1984 Apr;81(7):1991-5 PMID: 6326095
  7. Zinc-finger transcription factors in plants.
    Cell Mol Life Sci. 1998 Jun;54(6):582-96 PMID: 9676577
  8. A new family of zinc finger proteins in petunia: structure, DNA sequence recognition, and floral organ-specific expression.
    Plant Cell. 1994 Jul;6(7):947-58 PMID: 8069106
  9. Analysis of the 5' regulatory region of the gene for delta-aminolevulinic acid synthetase of Rhizobium meliloti.
    Nucleic Acids Res. 1985 Aug 26;13(16):5965-76 PMID: 2994020
  10. A Rhizobium meliloti homolog of the Escherichia coli peptide-antibiotic transport protein SbmA is essential for bacteroid development.
    Genes Dev. 1993 Aug;7(8):1485-97 PMID: 8393417
  11. Two classes of plant cDNA clones differentially complement yeast calcineurin mutants and increase salt tolerance of wild-type yeast.
    J Biol Chem. 1996 May 31;271(22):12859-66 PMID: 8662738
  12. Identification and characterization of the Rhizobium meliloti ntrC gene: R. meliloti has separate regulatory pathways for activation of nitrogen fixation genes in free-living and symbiotic cells.
    J Bacteriol. 1987 Apr;169(4):1423-32 PMID: 2881918
  13. Expression of nodule-specific genes in alfalfa root nodules blocked at an early stage of development.
    Genes Dev. 1988 Jun;2(6):677-87 PMID: 3417147
  14. Regulation of symbiotic root nodule development.
    Annu Rev Genet. 1998;32:33-57 PMID: 9928474
  15. The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family.
    Cell. 1989 Jul 14;58(1):133-45 PMID: 2526682
  16. Roles of plant homologs of Rab1p and Rab7p in the biogenesis of the peribacteroid membrane, a subcellular compartment formed de novo during root nodule symbiosis.
    EMBO J. 1993 Nov;12(11):4125-35 PMID: 8223429
  17. nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine.
    J Biol Chem. 1990 Jul 5;265(19):10857-64 PMID: 2358444
  18. A carbonic anhydrase gene is induced in the nodule primordium and its cell-specific expression is controlled by the presence of Rhizobium during development.
    Plant J. 1997 Mar;11(3):407-20 PMID: 9107031
  19. A bifunctional fusion between beta-glucuronidase and neomycin phosphotransferase: a broad-spectrum marker enzyme for plants.
    Gene. 1991 May 30;101(2):239-46 PMID: 1647361
  20. The indeterminate gene encodes a zinc finger protein and regulates a leaf-generated signal required for the transition to flowering in maize.
    Cell. 1998 May 15;93(4):593-603 PMID: 9604934
  21. Cys2/His2 zinc-finger protein family of petunia: evolution and general mechanism of target-sequence recognition.
    Nucleic Acids Res. 1998 Jan 15;26(2):608-15 PMID: 9421523
  22. Sequence requirements for synthetic peptide-mediated translocation to the nucleus.
    Mol Cell Biol. 1989 Jun;9(6):2487-92 PMID: 2668735
  23. Isolation and characterisation of a diverse family of Arabidopsis two and three-fingered C2H2 zinc finger protein genes and cDNAs.
    Plant Mol Biol. 1997 Mar;33(4):615-24 PMID: 9132053
  24. Rhizobium meliloti Genes Encoding Catabolism of Trigonelline Are Induced under Symbiotic Conditions.
    Plant Cell. 1990 Dec;2(12):1157-1170 PMID: 12354952
  25. ENOD12, an early nodulin gene, is not required for nodule formation and efficient nitrogen fixation in alfalfa.
    Plant Cell. 1994 Feb;6(2):201-13 PMID: 8148645
  26. Genes and signal molecules involved in the rhizobia-leguminoseae symbiosis.
    Curr Opin Plant Biol. 1998 Aug;1(4):353-9 PMID: 10066605
  27. Genetic studies on rhizobiophage 16-3. I. Genes and functions on the chromosome.
    Mol Gen Genet. 1973 Sep 27;125(4):341-50 PMID: 4777790
  28. A plant regulator controlling development of symbiotic root nodules.
    Nature. 1999 Nov 11;402(6758):191-5 PMID: 10647012
  29. Role of SUPERMAN in maintaining Arabidopsis floral whorl boundaries.
    Nature. 1995 Nov 9;378(6553):199-203 PMID: 7477325
  30. Characterization and mapping of human genes encoding zinc finger proteins.
    Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9563-7 PMID: 1946370
Article Info
Journal
Genes & development
Abbr.
Genes Dev
ISSN
0890-9369
Published
2000-02-15
Pages
475-82
Language
English
Region
United States
NLM ID
8711660
PMCID
PMC316383
Subset
IM
Databases
GENBANK
Y18788
External Links
PubMed source PMC Full Text View journal details
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