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PMID: 1064036 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The development of the action potential mechanism of amphibian neurons isolated in culture.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 73 ·No. 5 ·1976-05-00 ·Pages 1641-5

Spitzer NC, Lamborghini JE

Abstract

Nerve and muscle cells differentiated morphologically, in cultures of dissociated cells prepared from amphibian neural plate and underlying mesoderm (Xenopus laevis, Nieuwkoop and Faber stage 15). Cultures were grown in a defined medium containing sterile Steinberg's salt solution and 0.1% bovine serum albumin, and maintained for periods up to 5 days.

MeSH Terms
Action Potentials Age Factors Animals Biological Transport Calcium/metabolism Cells, Cultured Neurons/embryology,metabolism,physiology Sodium/metabolism Thymidine/metabolism Xenopus
Chemicals
Sodium Calcium Thymidine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Spitzer N C
Lamborghini J E
References (11)
11 references, click to expand
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    J Gen Physiol. 1966 Mar;49(4):793-806 PMID: 5943615
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    J Physiol. 1969 Nov;205(1):115-29 PMID: 5347712
  7. Tetrodotoxin sensitivity of cultured embryonic heart cells depends on cell interactions.
    J Cell Biol. 1973 Jan;56(1):255-8 PMID: 4682343
  8. The ionic basis of the resting potential and a slow depolarizing response in Rohon-Beard neurones of Xenopus tadpoles.
    J Physiol. 1976 Feb;255(1):105-35 PMID: 1255512
  9. Differentiation of amphibian embryonic cells in vitro.
    J Physiol. 1975 Mar;246(2):9P-10P PMID: 1142292
  10. Development of action potentials in a clonal rat skeletal muscle cell line.
    Nat New Biol. 1973 Jan 31;241(109):158-9 PMID: 4512622
  11. The influence of collagen on the development of muscle clones.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):119-26 PMID: 5220860
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.73.5.1641
Published
1976-05-00
Pages
1641-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC430355
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.73.5.1641 PMC Full Text View journal details
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