The Pfam protein families database.

Nucleic acids research ·Vol. 28 ·No. 1 ·2000-01-01 ·Pages 263-6

Bateman A, Birney E, Durbin R, Eddy SR, Howe KL, Sonnhammer EL

Abstract

Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the WWW in the UK at http://www.sanger.ac.uk/Software/Pfam/, in Sweden at http://www.cgr.ki.se/Pfam/ and in the US at http://pfam.wustl.edu/. The latest version (4.3) of Pfam contains 1815 families. These Pfam families match 63% of proteins in SWISS-PROT 37 and TrEMBL 9. For complete genomes Pfam currently matches up to half of the proteins. Genomic DNA can be directly searched against the Pfam library using the Wise2 package.

MeSH Terms

Databases, Factual Genome Information Storage and Retrieval Internet Proteins/chemistry Quality Control

Chemicals

Proteins

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Bateman A

The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. agb@sanger.ac.uk

Birney E

Durbin R

Eddy S R

Howe K L

Sonnhammer E L

References (12)

12 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/28.1.263

agb@sanger.ac.uk

Published

2000-01-01

Pages

263-6

Language

English

Region

England

NLM ID

0411011

PMCID

PMC102420

Subset

External Links

PubMed source DOI: 10.1093/nar/28.1.263 PMC Full Text View journal details

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