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PMID: 10592177 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The protein information resource (PIR).

Nucleic acids research ·Vol. 28 ·No. 1 ·2000-01-01 ·Pages 41-4

Barker WC, Garavelli JS, Huang H, McGarvey PB, Orcutt BC, Srinivasarao GY, Xiao C, Yeh LS, Ledley RS, Janda JF, Pfeiffer F, Mewes HW, Tsugita A, Wu C

Abstract

The Protein Information Resource (PIR) produces the largest, most comprehensive, annotated protein sequence database in the public domain, the PIR-International Protein Sequence Database, in collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japan International Protein Sequence Database (JIPID). The expanded PIR WWW site allows sequence similarity and text searching of the Protein Sequence Database and auxiliary databases. Several new web-based search engines combine searches of sequence similarity and database annotation to facilitate the analysis and functional identification of proteins. New capabilities for searching the PIR sequence databases include annotation-sorted search, domain search, combined global and domain search, and interactive text searches. The PIR-International databases and search tools are accessible on the PIR WWW site at http://pir.georgetown.edu and at the MIPS WWW site at http://www. mips.biochem.mpg.de. The PIR-International Protein Sequence Database and other files are also available by FTP.

MeSH Terms
Databases, Factual Information Storage and Retrieval Internet Proteins/chemistry,genetics
Chemicals
Proteins
Authors & Affiliations
14 authors, click to expand affiliations / ORCID
Barker W C
Protein Information Resource, National Biomedical Research Foundation, 3900 Reservoir Road, NW, Washington, DC 20007, USA. pirmail@nbrf.georgetown.edu
Garavelli J S
Huang H
McGarvey P B
Orcutt B C
Srinivasarao G Y
Xiao C
Yeh L S
Ledley R S
Janda J F
Pfeiffer F
Mewes H W
Tsugita A
Wu C
References (13)
13 references, click to expand
  1. PIR-ALN: a database of protein sequence alignments.
    Bioinformatics. 1999 May;15(5):382-90 PMID: 10366659
  2. MIPS: a database for genomes and protein sequences.
    Nucleic Acids Res. 2000 Jan 1;28(1):37-40 PMID: 10592176
  3. The RESID database of protein structure modifications: 2000 update.
    Nucleic Acids Res. 2000 Jan 1;28(1):209-11 PMID: 10592227
  4. ProClass protein family database.
    Nucleic Acids Res. 2000 Jan 1;28(1):273-6 PMID: 10592245
  5. The origin and evolution of protein superfamilies.
    Fed Proc. 1976 Aug;35(10):2132-8 PMID: 181273
  6. NRL-3D: a sequence-structure database derived from the protein data bank (PDB) and searchable within the PIR environment.
    Protein Seq Data Anal. 1990 Oct;3(5):387-405 PMID: 2259697
  7. The Protein Data Bank: Current Status and Future Challenges.
    J Res Natl Inst Stand Technol. 1996 May-Jun;101(3):231-241 PMID: 27805161
  8. Improved tools for biological sequence comparison.
    Proc Natl Acad Sci U S A. 1988 Apr;85(8):2444-8 PMID: 3162770
  9. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
    Nucleic Acids Res. 1994 Nov 11;22(22):4673-80 PMID: 7984417
  10. The PIR-International databases.
    Nucleic Acids Res. 1993 Jul 1;21(13):3089-92 PMID: 8332528
  11. Superfamily classification in PIR-International Protein Sequence Database.
    Methods Enzymol. 1996;266:59-71 PMID: 8743677
  12. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.
    Nucleic Acids Res. 1997 Sep 1;25(17):3389-402 PMID: 9254694
  13. MView: a web-compatible database search or multiple alignment viewer.
    Bioinformatics. 1998;14(4):380-1 PMID: 9632837
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
Published
2000-01-01
Pages
41-4
Language
English
Region
England
NLM ID
0411011
PMCID
PMC102418
Subset
IM
Grants
NLM NIH HHS · P41 LM05978 · United States
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