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PMID: 10549246 Published · ppublish English Historical Article Journal Article

Further studies on fecal parasites in antiquity.

American journal of clinical pathology ·Vol. 112 ·No. 5 ·1999-11-00 ·Pages 605-9

Allison MJ, Bergman T, Gerszten E

Abstract

This is a continuation study of the survival of antigenic material over the centuries using mummified human remains from the Andean area of South America. The fluorescent antibody kit from Meridian Diagnostics (Cincinnati, OH) was used to identify some Cryptosporidium species and Giardia species found in feces from the intestines of mummies 500 to 3,000 years old. The specimens that were positive by direct visualization using fluorescent antibody were then tested with an enzyme-linked immunosorbent assay reaction using a Meridian kit just released on the market. Since all of the feces used were formed, it would seem that the organisms found were from carriers rather than active cases of disease. Similar fecal specimens were shown to harbor antigens from Helicobacter pylori almost 3,000 years old.

MeSH Terms
Animals Antibodies, Protozoan/immunology Antigens, Protozoan/analysis Cryptosporidiosis/history,parasitology Cryptosporidium/immunology,isolation & purification Enzyme-Linked Immunosorbent Assay Feces/parasitology Fluorescent Antibody Technique, Direct Giardia/immunology,isolation & purification Giardiasis/history,parasitology History, Ancient History, Medieval Humans Indians, South American/history Mummies Paleopathology Reagent Kits, Diagnostic South America
Chemicals
Antibodies, Protozoan Antigens, Protozoan Reagent Kits, Diagnostic
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Allison M J
Department of Pathology, Virginia Commonwealth University, Richmond 23237, USA.
Bergman T
Gerszten E
Article Info
Journal
American journal of clinical pathology
Abbr.
Am J Clin Pathol
ISSN
0002-9173
Published
1999-11-00
Pages
605-9
Language
English
Region
England
NLM ID
0370470
Subset
IM
Corrections
CommentIn
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