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PMID: 104 Published · ppublish rus English Abstract Journal Article

[Level of nicotinamide coenzymes in the liver and myocardium of rats poisoned with dichlorethane].

Soderzhanie nikotinamidnykh kofermentov v pecheni i miokarde krys, otravlennykh dikhlorétanom

Biulleten' eksperimental'noi biologii i meditsiny ·Vol. 79 ·No. 4 ·1975-04-00 ·Pages 58-60

Natsiuk MV, Chekman IS

Abstract

Experiments were conducted on male rats. A study was made of the content of nicotinamide coenzymes in the liver and myocardium 24 hours after the administration of 0.5 ml of dichloroethane into the stomach. In parallel with disturbance of the morphological structure of the liver and of the myocardium, increase in the activity of alanine and aspargic aminotranspherases in the blood serum, dichloroethane reduced the content of nicotinamide coenzymes and deranged the ratio of their oxidized and reduced forms in these organs.

MeSH Terms
Alanine Transaminase/blood Animals Aspartate Aminotransferases/blood Ethylene Dichlorides/poisoning Heart/drug effects Hydrocarbons, Chlorinated/poisoning Liver/drug effects,metabolism Male Myocardium/metabolism NAD/metabolism NADP/metabolism Rats
Chemicals
Ethylene Dichlorides Hydrocarbons, Chlorinated NAD NADP Aspartate Aminotransferases Alanine Transaminase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Natsiuk M V
Chekman I S
Article Info
Journal
Biulleten' eksperimental'noi biologii i meditsiny
Abbr.
Biull Eksp Biol Med
ISSN
0365-9615
Published
1975-04-00
Pages
58-60
Language
rus
Region
Russia (Federation)
NLM ID
0370627
Subset
IM
Grants
Medical Research Council · G0502121 · United Kingdom
External Links
PubMed source
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