Purification and assays for high mobility group HMG-I(Y) protein function.

Animals Base Sequence Cell Fractionation/methods Cell Nucleus/chemistry,ultrastructure Centrifugation/methods Chromatin/chemistry,ultrastructure Chromatography, High Pressure Liquid/methods Chromatography, Ion Exchange/methods DNA Footprinting/methods DNA, Superhelical/chemistry,isolation & purification,metabolism Deoxyribonuclease I HMGA1a Protein HeLa Cells High Mobility Group Proteins/analysis,isolation & purification,metabolism Humans Indicators and Reagents Interleukin-4/genetics Leukemia, Erythroblastic, Acute/metabolism,pathology Mice Molecular Sequence Data Mutagenesis, Site-Directed Neoplasm Proteins/isolation & purification Plasmids Receptors, Interleukin-2/genetics Recombinant Proteins/analysis,isolation & purification,metabolism Transcription Factors/analysis,isolation & purification,metabolism Transfection Tumor Cells, Cultured

Chromatin DNA, Superhelical High Mobility Group Proteins Indicators and Reagents Neoplasm Proteins Receptors, Interleukin-2 Recombinant Proteins Transcription Factors HMGA1a Protein Interleukin-4 Deoxyribonuclease I