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PMID: 10209113 Published · ppublish English Journal Article Review

Basement membranes: Putting up the barriers.

Current biology : CB ·Vol. 9 ·No. 7 ·1999-04-08 ·Pages R242-4

Schwarzbauer J

Abstract

The basement membrane is a highly organized extracellular matrix with adhesive and barrier functions. Assembly of this matrix uses two types of cell surface receptor, integrins and dystroglycan, to coordinate formation of a polygonal network of laminin, a major basement membrane protein.

MeSH Terms
Animals Basement Membrane/physiology Cell Membrane/metabolism Cytoskeletal Proteins/metabolism Dystroglycans Extracellular Matrix/physiology Humans Integrins/metabolism Membrane Glycoproteins/metabolism
Chemicals
Cytoskeletal Proteins DAG1 protein, human Integrins Membrane Glycoproteins Dystroglycans
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Schwarzbauer J
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014, USA. jschwarzbauer@molbio.princeton.edu
Article Info
Journal
Current biology : CB
Abbr.
Curr Biol
ISSN
0960-9822
DOI
10.1016/s0960-9822(99)80153-5
Email
jschwarzbauer@molbio.princeton.edu
Published
1999-04-08
Pages
R242-4
Language
English
Region
England
NLM ID
9107782
Subset
IM
External Links
PubMed source DOI: 10.1016/s0960-9822(99)80153-5 View journal details
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