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PMID: 10098400 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Non-mitochondrial ATP transport.

Trends in biochemical sciences ·Vol. 24 ·No. 2 ·1999-02-00 ·Pages 64-8

Winkler HH, Neuhaus HE

Abstract

Exchange of organelle ATP with cytosolic ADP through the ADP/ATP carrier is a well-characterized feature of mitochondrial metabolism. Obligate intracellular bacteria, such as Rickettsia prowazekii, and higher-plant plastids possess another type of adenylate transporter, which exchanges bacterial or plastidic ADP for ATP from the eukaryotic (host cell) cytoplasm. The bacterial and plastidic transporters are similar but do not share significant sequence similarities with the mitochondrial carrier. Recent molecular and biochemical studies are providing deeper insight into the functional and evolutionary relationships between the bacterial and the plant transport proteins.

MeSH Terms
Adenosine Triphosphate/metabolism Amino Acid Sequence Bacteria/metabolism Biological Transport, Active Mitochondria/metabolism Mitochondrial ADP, ATP Translocases/genetics,metabolism Molecular Sequence Data Organelles/metabolism Plastids/metabolism Sequence Homology, Amino Acid
Chemicals
Adenosine Triphosphate Mitochondrial ADP, ATP Translocases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Winkler H H
Dept of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile 36688, USA. herbertw@sungcg.usouthal.edu
Neuhaus H E
Article Info
Journal
Trends in biochemical sciences
Abbr.
Trends Biochem Sci
ISSN
0968-0004
Published
1999-02-00
Pages
64-8
Language
English
Region
England
NLM ID
7610674
Subset
IM
Grants
NIAID NIH HHS · AI-15035 · United States
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